Therapeutic Group: Mineral & Vitamin Preparations
Cocavit DX® 600 mg/400 IU
Tablet: Each tablet contains 1500 mg of Coral Calcium Carbonate USP equivalent
to 600 mg of elemental Calcium and 400 IU as Cholecalciferol USP equivalent to
Vitamin D3. Cocavit DX® has been manufactured as an easy to swallow formulation.
Cocavit D® & Cocavit DX® provides Calcium and Vitamin D3 where Calcium Carbonate is sourced from Coral origin. The Calcium Carbonate from Coral has a chemical structure that is very similar to the composition of human bone. Coral Calcium is similar to other sources but ensures better absorption.
Vitamin D3 aids in the
absorption of Calcium from GI tract and helps to maintain Calcium balance in
the body.
Calcium and Vitamin D3 is
indicated for the treatment and prevention of Osteoporosis, Osteomalacia,
Tetany, Hypoparathyroidism, Disorders of Osteogenesis. Also used as supplement
in case of inadequate intake of Calcium in childhood diet, rickets, pregnancy
& lactation, elderly patients. Other indications include pancreatitis,
phosphate binder in chronic renal failure etc.
One tablet of Cocavit DX®
is once or twice daily with plenty of water or as directed by the physician.
Taking in full stomach ensures better absorption.
Flatulence, diarrhoea,
constipation, upper GI discomfort etc. are rare manifestation. Hypercalcaemia
due to prolong use has rarely been reported.
In presence of mild
hypercalciuria, careful monitoring with reduction of dose may be needed. Plasma
and serum calcium level should be monitored in mild to moderate impairment and
also in case of long-term use. Patients with renal stone or with such previous,
history should also take precaution.
Oral calcium can reduce
the absorption of tetracycline & fluoride preparations and minimum 3 hours
should be allowed between ingestion of these medications. Thiazide diuretics
reduces the renal excretion of calcium. Phenytoin, barbiturates, glucocorticoids
may induce metabolism of Vitamin D3. Concomitant ingestion of certain foods
like spinach, cereals, milk and its derivatives may reduce the intestinal
uptake of Calcium.
At high doses it may
result in nausea, vomiting, dizziness, anorexia, abdominal cramps, headache,
constipation, irritability etc. Treatment includes cessation of therapy and
adequate rehydration.
Store at temperature of
below 30° C. Protect from light.
Cocavit DX® 600 mg/400 IU
Tablet: Each box contains 3X10 tablets in Alu-PVDC blister strips.