Aceflex

Aceflex® 100 mg Tablet: Each film-coated tablet contains Aceclofenac BP 100 mg.

Aceflex® (Aceclofenac) is a non-steroidal agent with marked anti-inflammatory and analgesic properties. It is a potent inhibitor of the enzyme cyclooxygenase, which is responsible for the production of prostaglandin. After oral administration, Aceclofenac is rapidly and completely absorbed as unchanged drug. Peak plasma concentrations are reached approximately 1.25 to 3 hrs following ingestion.

For the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, post-traumatic pain, low back pain, gynecological pain etc.

1. Adults: The recommended dose is 100 mg (1 tablet), twice daily, one in the morning and one in the evening.
2. Children: There are no clinical data on the use of Aceclofenac in children.
3. Elderly: The pharmacokinetics of Aceclofenac is not altered in elderly patients, therefore it is not considered necessary to modify the dose or dose frequency.

Aceclofenac should be administered with caution to patients with symptoms indicative of gastrointestinal disorders, with a history of peptic ulceration, ulcerative colitis, Crohn’s disease, hepatic porphyria and coagulation disorders. Patients suffering from severe hepatic impairment must be monitored.

1. Lithium & digoxin: Aceclofenac like many NSAIDs, may increase plasma concentrations of lithium and digoxin.
2. Diuretics: Aceclofenac, like other NSAIDs, may inhibit the activity of diuretics.
3. Anticoagulants: Like other NSAIDs Aceclofenac may enhance the activity of anticoagulants. Close monitoring of patients on combined anticoagulant and aceclofenac therapy should be undertaken.

Store at temperature not exceeding 30º C in a dry place. Protect from light.

Aceflex® 100 mg Tablet: Each box contains 5X10's tablets in Alu-PVC blister strips.